O uso de probióticos no tratamento do transtorno depressivo: uma revisão de ensaios clínicos randomizados

Abstract

Objective: To analyze the use of probiotics in the treatment of depressive disorder. Method: Articles were searched from two data bases: National Library of Medicine (PUBMED) and BVS Regional Portal (BIREME). The search for data obey the following filters and inclusion criteria: articles of the clinical trial type, carried out with adolescents, adults and elderly of both sexes, from the last 10 years, in English and Portuguese. The final sample was nine articles. Results: The administration of probiotics promotes a decrease in negative thoughts, cognitive reactivity and improvement in symptoms of depression and anxiety. Conclusions: The use of probiotics may be an interesting complement in the treatment of depressive disorder; however, because the studies presented the use of different strains and amounts of probiotics, more studies are needed to safely infer about their use and the relationship between gut microbiota and mental health.