Doença celíaca: uma revisão sistemática sobre os efeitos da intervenção terapêutica com probióticos

Abstract

Objective: to analyze the intervention with probiotics in celiac disease, in order to contribute to a more efficient protocol in the treatment of this disorder. Methods: systematic review of articles published between 2013 and 2020, which summarized the evidence related to the impact of probiotic administration on celiac disease. Results: 10 studies were included, the largest intervention was in the female audience (n = 1,281), ranging in age from 3 months to 74 years; studies that divided patients into groups; probiotic and placebo (n = 4), probiotic, placebo and control group (n = 2); celiac and healthy patients (N = 1); investigated the use of probiotics in genetically susceptible children (n = 1); He observed the use of the symbiotic in patients with CD (n = 1); analysis of the effects of probiotics in patients at genetic risk for CD (n = 1). Conclusion: probiotics are beneficial for celiac patients and children genetically at risk of this disease, associated with a gluten-free diet.