O papel da vitamina D nas doenças inflamatórias intestinais

Abstract

Introduction: Inflammatory Bowel Diseases (IBD) are inflammatory and chronic diseases that affect the gastrointestinal tract (GIT), the most common being Crohn's Disease (CD) and Ulcerative Colitis (RU). Vitamin D is totally related to these diseases, as deficiency in these patients is very common, due to a series of factors. Objective: Check the consequences of this deficiency and what are the benefits brought by the appropriate levels and supplementation. Methods: Search performed in the databases: Scientific Electronic Library Online (Scielo), US National Library of Medicine (PubMed) and Latin American and Caribbean Literature in Health Sciences (LILACS), through the Virtual Health Library (VHL) portals , Capes Journals and Google Scholar using the descriptors: Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis, Vitamin D Deficiency. Results: Eleven articles were included that demonstrate the prevalence of deficiency in females and that low vitamin D leads to cancer risk and low bone mineral density. Adequate levels associated with supplementation showed less active disease and decreased inflammatory markers. Conclusion: It is concluded that adequate levels of vitamin D have positive effects on patients with IBD and that routine tests are necessary to monitor these dosages.