Suplementação de curcumina em indivíduos com diabetes ou pré-diabetes: uma revisão de literatura

Abstract

Diabetes Mellitus (DM) is a disease that has been growing over the years, along with the search for its best treatment and prevention. It has been studied that food sources of phytochemicals, especially curcumin, have properties that help in the health of individuals with DM. Objective: to evaluate the effects of curcumin consumption on DM prognosis and glycemic control in diabetic or pre-diabetic individuals. Method: a literature review of original clinical trials published from 2012 to 2022 was performed, which evaluated the effect of curcumin supplementation on DM prognosis and glycemic control in diabetics and pre-diabetics. Results: most articles (n = 8/10) showed a significant reduction in glycemic indexes (glycemia and glycated hemoglobin) and BMI of participants in the group that received curcumin treatment, with dosages from 250 to 1.500 mg, along with changes in diet and physical activity habits, compared to the group who received a placebo. In addition, some articles showed positive changes in the lipid profile of the individuals, while those who used dosage below the presented range did not observe effects on glycemic markers between the groups. Conclusion: The consumption of curcumin helped in glycemic control and generated positive results in improving the lipid profile of the participants.