O uso do inositol como tratamento dietético da síndrome do ovário policístico: uma revisão da literatura

Abstract

Polycystic Ovary Syndrome (PCOS) is characterized by enlargement of the ovaries with stromal hypertrophy and several cysts in the cortex. It is considered the main cause of anovulatory infertility, leading to an increase in diseases such as dyslipidemia, hypertension, type 2 diabetes, metabolic syndrome and endothelial dysfunction, also leading to an increase in cardiovascular diseases, in addition to the various associated symptoms. It is known that insulin plays a determining role in the pathophysiology of the disease, which is why Inositol is increasingly being used as an option in the treatment of PCOS. Thus, the objective of the present study was to evaluate the use of inositol in the dietary treatment of patients with PCOS. The present study is a literature review using the PubMed, Scopus and Web of Science databases, considering articles from the last ten years in English and Portuguese on the topic of the use of inositol in the treatment of PCOS. The authors selected for the study adopted several strategies for treating PCOS, from contraceptive medication to the use of diet and inositol. The interventions, however, still need to be studied more carefully to conclude their effectiveness. This work also observed that contraceptive treatments and the use of inositol present positive results, as well as changes in lifestyle habits and diet composition. Thus, it is concluded that inositol is the closest intervention to the drug interventions with the best results presented. Its dosage, frequency and time of use still requires more evidence.