Os efeitos da suplementação de creatina na função cognitiva: uma revisão de literatura

Abstract

Objective: review the effects of creatine supplementation on aspects related to human cognition. Methods: a literature review was carried out using only original articles, of the randomized clinical trial type, which aimed to review the effect of creatine supplementation on cognitive aspects, performed in adults and elderly, published in Portuguese and English, in the last 10 years. Results: All studies suggest that creatine supplementation was safe and well tolerated by the samples. Promoted improvement in cognition tests and energy metabolism of the central nervous system, in addition to improvement in verbal fluency and significant changes in brain anatomy and white matter integrity in specific groups. However, in about a third of the evaluated clinical trials, no alterations were observed in cognitive aspects of supplemented individuals. Conclusion: creatine supplementation promoted positive effects in aspects related to cognition. It has not yet been possible to show how alterations in structures, energy metabolism or even in a marker of executive function of the central nervous system can influence an individual's general cognitive performance.