MICROBIOTA INTESTINAL E SUA RELAÇÃO COM A PELE E O SOBREPESO

Abstract

The intestinal microbiota has been widely studied for its influence on systemic health, playing a fundamental role in the modulation of the immune system, inflammation and metabolism. This study constitutes a narrative literature review that aims to analyze the relationship between the composition of the intestinal microbiota, dermatological conditions and the development of overweight. Scientific evidence suggests that microbiota imbalance, known as dysbiosis, may contribute to skin disorders such as acne, atopic dermatitis and psoriasis, through the gut-skin axis, which involves complex interactions between the immune system, the systemic inflammatory state and the integrity of the intestinal barrier. In parallel, evidence indicates that dysbiosis contributes to obesity-related metabolic alterations, including insulin resistance, increased intestinal permeability and activation of pro-inflammatory pathways, involving immunological and inflammatory mechanisms. The review indicates that strategies such as the use of probiotics, prebiotics and dietary changes can benefit both skin health and weight control, reinforcing the importance of the intestinal microbiota as a multidisciplinary therapeutic target.

Keywords: intestinal microbiota, dysbiosis, gut-skin axis, obesity, skin health, probiotics.