IMPACTOS ACERCA DOS FATORES DE COAGULAÇÃO, ANTES, DURANTE E APÓS A PANDEMIA DE COVID-19

Abstract

Objective: To evaluate the impacts on blood coagulation factors in patients from the clinical laboratory of PUC Goiás (LAC-PUC GO) before, during, and after the COVID-19 pandemic, focusing on parameters such as Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), and platelet count. Methods: This is a cross-sectional study in which 10,563 medical records were collected. After filtering and analysis, 347 viable patient records were selected from those treated at the laboratory between January and March in the years 2020, 2021, and 2022. PT, APTT, and platelet counts were analyzed, comparing the results between different pandemic periods and age groups. Results: Significant variations were observed in coagulation times and platelet counts, especially among age and sex groups. Younger patients, particularly women, exhibited greater variability in the analyzed parameters. There was a downward trend in platelet counts among elderly patients over the three periods analyzed. Conclusion: The COVID-19 pandemic significantly affected blood coagulation parameters, with important clinical implications for the management of patients with this viral disease and possible coagulopathies. Continuous monitoring of these parameters is essential for the early detection of complications.