ASSOCIAÇÃO DA ALTERAÇÃO GLICÊMICA AO PERFIL LABORATORIAL DE INFECÇÃO URINÁRIA: UM LEVANTAMENTO DE DADOS NO LABORATÓRIO CLÍNICO DA PONTIFÍCIA UNIVERSIDADE CATÓLICA DE GOIÁS

Abstract

Introduction: Urinary tract infection (UTI) represents the most prevalent form of bacterial infection, spanning all age groups. The notable prevalence of key infectious agents causing this condition in patients with Diabetes Mellitus (DM) suggests a potential influence of 5 hyperglycemia on susceptibility to urinary tract infections. Methodology: This is a cross- sectional analytical study with a comparative group design. The following tests were employed for analysis: fasting blood glucose, glycated hemoglobin, glucose tolerance test, and urine culture, correlated through statistical tests for data construction and correlation. Results and Discussion: In this study involving 7653 patients, 723 had positive urine cultures. There was a female predominance (73.8%), especially among the elderly, related to factors such as sexual activity, previous history of UTI, and female anatomical characteristics. Additionally, urogenital surgeries, conditions like incontinence and cystocele, as well as reduced estrogen post-menopause, contribute to the vulnerability of elderly women. Among patients with positive urine cultures, 41.4% had altered glycemia, with an average of 108.96 mg/dL. This data is likely related to immunosuppression and autonomic neuropathy, affecting bladder emptying. Escherichia coli was the most common agent (70.4%), and the patients' average blood glucose levels were above the normoglycemic threshold. Conclusion: The findings underscore the importance of effective strategies for prevention, diagnosis, and treatment of UTIs in diabetic patients.