Tipo:	Trabalho de Conclusão de Curso
Título:	Use of vincristine for the treatment of postherpetic neuralgia: case report
Autor(es):	Peleja, Jaqueline de Pádua Castro, Sophia Proto de
Primeiro Orientador:	Silva, Ledismar José da
metadata.dc.contributor.referee1:	Carneiro, Lórimer Sandoval
Resumo:	Chronic pain is a condition that can cause prolonged physical and emotional suffering, affecting several aspects of an individual's life. To be considered chronic, the pain must last for at least three months and be associated with notable emotional distress and/or functional disability, which can lead to social isolation and a feeling of hopelessness. In the present study, a specific type of chronic pain is approached. The Herpes zoster virus, which causes varicella, popularly known as chickenpox, can persist in a latent state in the nervous system after a primary infection. It can later lead to an infection resulting from virus reactivation, named Herpes zoster and also known as shingles, which may be followed by postherpetic neuralgia, a persistent pain that can last for more than three months after the resolution of the skin lesions caused by the virus reactivation. This study aimed to report the possibility of treating refractory post-herpetic neuralgia with the antineoplastic drug vincristine sulfate, which can be applied off-label in patients presenting with pain caused by other illnesses besides tumors. It is important to emphasize that the use of vincristine for the treatment of postherpetic neuralgia requires care and should only be performed by specialist physicians after a detailed evaluation of the patient's clinical condition.
Palavras-chave:	Chronic pain Herpes zoster Postherpetic neuralgia
CNPq:	CNPQ::CIENCIAS DA SAUDE
Idioma:	por
País:	Brasil
Editor:	Pontifícia Universidade Católica de Goiás
Sigla da Instituição:	PUC Goiás
metadata.dc.publisher.department:	Escola de Ciências Médicas e da Vida
Tipo de Acesso:	Acesso Aberto
URI:	https://repositorio.pucgoias.edu.br/jspui/handle/123456789/7323
Data do documento:	18-Mai-2023
Aparece nas coleções:	TCC Medicina

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