A genética do transtorno do espectro autista (TEA): uma revisão bibliográfica

Abstract

It is understood that autism is a multifactorial disorder that interferes with the social, verbal and behavioral communication of the individual with it, whether due to environmental, neural and genetic factors. The objective of this work was to understand how the disease was discovered, its history of current definition, its manifestations, types, heritability and mainly which are the main genetic factors (genes and proteins) altered. The research was carried out through articles on the genomic activity composed of people of both sexes, who were diagnosed with autism spectrum disorder. This study aimed to reiterate the importance of the association of genetic factors in patients within the autistic spectrum, in which it revealed the relationship between some regions of the chromosomes with the predominant sex, degrees of severity and with the central nervous system that presents a connection with verbal and behavioral manifestations.