Uso de infusão de cetamina intravascular para o tratamento de dor crônica e depressão: relato de caso

Abstract

Chronic pain and depression are two comorbidities that correlate at the molecular level in the central nervous system and cause suffering to the patient, being difficult to manage. Ketamine, a widely known anesthetic derived from phenicyclidine with analgesic, sedative and antipsychotic properties, is a promising option for the treatment of these two diseases by acting, among other sites, on the NMDA receptor, responsible for the sensory input. In this report, we discuss the case of a patient with refractory interstitial cystitis for 13 years to the management of pain and depression, who underwent serial infusions of intravascular ketamine.