Impactos do uso prolongado de anticoncepcionais hormonais na saúde da mulher: uma revisão atualizada

Abstract

Introduction: Hormonal contraceptives are widely used in pregnancy prevention and women's health therapy; however, their prolonged use may be associated with systemic and local repercussions. Objective: To analyze the main impacts related to the prolonged use of these drugs on women's health through an integrative literature review. Method: 28 articles published between 2016 and 2026 were analyzed, selected from the Virtual Health Library (VHL), PubMed, and SciELO databases, using the DeCS (Hormonal Contraceptives) and MeSH (Contraceptives, Oral, Hormonal) descriptors. Results: The analyzed studies show an association between the prolonged use of hormonal contraceptives and laboratory, metabolic, cardiovascular, neurological, sexual, and immunological alterations, as well as possible associations with thromboembolic events, neoplasms, and alterations in the vaginal microbiota. Individual factors, clinical conditions, and the type of formulation influence the response to treatment. In conclusion, clinical and laboratory monitoring, combined with individualized choice of contraceptive method, are essential to minimize risks and promote the safe use of these drugs. KEYWORDS: Hormonal Contraceptives; Women's Health; Side Effects; Adverse Reactions.