Psoríase e o aumento da glicose circulante - relações metabólicas e clínicas

Abstract

Psoriasis is a chronic dermatological disease characterized as a painful, inflammatory, hyperproliferative, autoimmune, non-contagious condition that shows no preference for gender or age. It goes beyond visible skin manifestations and has a direct relationship with metabolic alterations related to circulating glucose. Scientific evidence shows that glycemic imbalance influences the progression of the disease by interfering with inflammatory and immunological processes. This study clearly and objectively addresses this interaction, highlighting the connection between cutaneous and metabolic mechanisms through a narrative review involving exploratory research in the SciELO, PubMed, Google Scholar, CAPES Portal, and MEDLINE databases. Psoriasis should not be understood merely as an isolated dermatological disease, but as a systemic condition that is closely related to metabolic disorders caused by changes in circulating glucose — a factor that may trigger the worsening of symptoms. Understanding the interaction between dermatological, metabolic, and cardiovascular factors is essential for the proper clinical management of Psoriasis, reinforcing the need for interdisciplinary follow-up and for prevention and control strategies that prioritize the patient's overall health.