Impacto e caracterização dos estudos nacionais sobre os efeitos biológicos da radiação ionizante

Abstract

Given its highly hazardous nature, the use of protective methods and personal protective equipment (PPE) is essential when dealing with ionizing radiation. These protective measures are mandatory in settings such as medical and nuclear environments. Therefore, it is necessary to know, understand, and critically analyze the scientific literature on this topic. This study aimed to conduct an integrative systematic review of the literature on national studies investigating ionizing radiation and its cellular implications. Ten scientific articles, published between 2020 and 2024 in Brazil, were selected from the Scopus database. The study highlights that the selected publications were divided into four main themes: radiation resistance in glioblastoma, the DNA damage response in protozoa, the effects of radiation on experimental models, and damage from diagnostic radiation. The analysis also reveals the dominance of the Southeast region in terms of publications, with the University of São Paulo (USP) being the most prominent institution. Overall, the studies highlight a gap in national scientific production in other regions of the country, reflecting the low investment in research, since studies in this area require laboratories, equipment, specialized researchers, and significant funding for the proper execution of scientific production.