BRCA1 nos efeitos colaterais tardios da radioterapia em pacientes portadoras de câncer de mama

Abstract

The late effects of radiotherapy can manifest themselves months or years after the end of treatment, however studies are still needed to highlight the factors that can predict their occurrence and incidence. The present study reviewed the literature on clinical and genetic factors and the incidence of adverse events described after radiotherapy for breast cancer. There was a wide variation in the incidence of late effects of radiotherapy and there is no clarity about the clinical or genetic factors associated with their higher incidence in subgroups of patients.