Prevalência de infecção por klebsiella pneumoniae em unidades de terapia intensiva (UTI'S) adulto: revisão de literatura

Abstract

Introduction: Klebsiella pneumoniae infections have increased in intensive care units (ICUs) in the last decade. These infections represent a serious problem, especially when there is antimicrobial resistance. Objective: According to the literature, determine the prevalence of infections caused by K. pneumoniae in adult ICU patients. Methodology: This study is a literature review. The search was carried out through the selection and analysis of scientific articles indexed in the PubMed, Scopus, SciELO. The search period was established between the years 2020 to 2024 covering the last five years. Results: K. pneumoniae is responsible for complex and difficult-to-manage hospital-acquired infections, including sepsis, urinary tract infections, catheter-associated infections, pneumonia, and surgical site infections in intensive care units. The main challenge in infections caused by K. pneumoniae is the scarcity of treatment alternatives, as there is significant resistance to several antibiotics, which results in an increase in morbidity and mortality rates. Inappropriate and excessive use of carbapenems can result in outbreaks that are difficult to manage, especially in intensive care units, due to the development of resistance to this group of antibiotics. Conclusion: In recent years, outbreaks and isolated cases of carbapenem-resistant K. pneumoniae (CRKP) have been recorded in several parts of the world, with an increasing frequency.