https://repositorio.pucgoias.edu.br/jspui/handle/123456789/77 Sun, 18 Oct 2026 16:21:12 GMT 2026-10-18T16:21:12Z https://repositorio.pucgoias.edu.br/jspui/handle/123456789/11176 Título: Impactos dos níveis de vitamina D sobre os auto anticorpos de pacientes com doença de Hashimoto Abstract: Abstract: Hashimoto's thyroiditis (HT) is the most common form of autoimmune thyroid disease and is characterized by the progressive destruction of thyroid follicular cells, frequently leading to hypothyroidism. In recent years, vitamin D has been extensively investigated due to its immunomodulatory role and its possible relationship with the autoimmune activity of the disease. This study aimed to analyze the impacts of serum vitamin D levels on thyroid autoantibodies in patients with Hashimoto's thyroiditis, especially the anti-TPO antibody, as well as to investigate its relationship with alterations in thyroid function. This is a systematic review conducted according to the PRISMA 2020 guidelines, using articles published between 2016 and 2026 in the PUBMED database. Thirteen studies were selected after eligibility criteria. The results demonstrated that most studies identified a trend of negative correlation between serum vitamin D levels and thyroid autoantibody titers, mainly anti-TPO and anti-TG, suggesting a possible association between vitamin D deficiency and increased autoimmune activity. Some studies also observed a relationship between vitamin D deficiency and hormonal changes consistent with greater impairment of thyroid function, such as elevated TSH and reduced levels of FT3 and FT4. However, some studies did not find statistically significant associations, highlighting discrepancies in the scientific literature. It is concluded that vitamin D may play a relevant role in the pathophysiology and immunological modulation of Hashimoto's thyroiditis, although 2prospective and methodologically standardized studies are still needed to clarify its reais influence on the disease and the potential therapeutic benefit of vitamin supplementation. Keywords: Hashimoto's thyroiditis; vitamin D; hypothyroidism; anti-TPO; thyroid autoantibodies; autoimmune diseases. Tipo: Trabalho de Conclusão de Curso Wed, 27 May 2026 00:00:00 GMT https://repositorio.pucgoias.edu.br/jspui/handle/123456789/11176 2026-05-27T00:00:00Z https://repositorio.pucgoias.edu.br/jspui/handle/123456789/11123 Título: Interseccionalidade e marcadores sociais da diferença no acesso à saúde: panorama da produção científica Abstract: Introduction: Intersectionality and social markers of difference—such as race, gender, class, and territory—shape asymmetries in access to fundamental rights. In the Brazilian health landscape, the overlapping of these forms of oppression creates systemic inequities that challenge the SUS principles of universality and equity, making intersectional analysis indispensable for formulating effective public policies. Objectives: To analyze, from an intersectional perspective, how the interplay of axes of oppression influences access to healthcare and perpetuates inequalities in Brazil, by mapping scientific literature, public policies, and the national epidemiological context. Methods: A systematic literature review (using a mixed-methods approach) was conducted following PRISMA 2020 guidelines and the PCC strategy. Searches were performed in January 2026 across the SciELO, PubMed, Scopus, Web of Science, and LILACS databases (covering the 2015–2025 period). Following screening on the Rayyan platform, 43 studies were selected for thematic synthesis. Results: An expanding body of research was observed—93% of which was domestic, peaking in 2025—with a central focus on the triad of race, gender, and class, appearing in over 70% of the sample. Intersectionality was primarily employed as an analytical tool within Primary Health Care, highlighting gaps between the formal guarantee of rights and the lived experiences of vulnerable populations (Black, *quilombola*, LGBTQIA+, and people experiencing homelessness). Discussion: Structural racism and heteronormativity act as determinants of inequity, fostering institutional violence and invisibility within information systems. The data confirm the "inverse care law," wherein highly vulnerable groups—such as Black women from marginalized urban areas and migrants—receive less care, underscoring the chasm between the legal framework and actual care delivery. Conclusion: Intersectionality represents an ethical-political imperative for the reorientation of the SUS. To realize constitutional principles, an intellectual transformation in professional training, improved quality in the collection of sociodemographic data, and the intersectional integration of public policies are urgently needed, aiming for an egalitarian health system consistent with human dignity. Tipo: Trabalho de Conclusão de Curso Mon, 01 Jun 2026 00:00:00 GMT https://repositorio.pucgoias.edu.br/jspui/handle/123456789/11123 2026-06-01T00:00:00Z https://repositorio.pucgoias.edu.br/jspui/handle/123456789/11122 Título: Emergências psiquiátricas, humanização e desafios contemporâneos no contexto da saúde: uma revisão integrativa da literatura Abstract: Psychiatric emergencies are acute crisis situations requiring immediate, technically qualified responses from health services. According to the World Health Organization, approximately 970 million people — about one in eight — live with a mental disorder worldwide, and demand for psychiatric emergency care has grown substantially over the past decade, placing pressure on systems largely not designed to receive these individuals with dignity. This study analyzed the technical-scientific literature on psychiatric emergencies published between 2020 and 2025, focusing on contemporary challenges to humanized care and strategies documented in the literature. An integrative review with thematic narrative synthesis was conducted according to the PRISMA 2020 protocol. Searches were performed in PubMed/MEDLINE, BVS/LILACS and BDENF, and SciELO, between January and April 2026. A total of 287 records were identified; after removing 21 duplicates, 266 were screened by title and abstract. Of these, 184 were excluded at initial screening. The remaining 82 articles underwent full-text assessment; 20 were excluded with documented reasons, yielding a final corpus of 62 studies from 16 countries. Thematic synthesis was organized into seven axes: humanization in psychiatric emergencies; coercive practices and restraint; structural weaknesses and organizational barriers; COVID-19 pandemic impacts; therapeutic communication and person-centered care; public policies and Psychosocial Care Network (RAPS); and professional training, stigma, and specific vulnerabilities. Findings indicate that dehumanizing care in psychiatric emergency settings stems primarily from structural and organizational conditions consistently identified across different countries and health systems, rather than from individual professional failures. The COVID-19 pandemic exacerbated pre-existing vulnerabilities and deepened inequalities in access to care. Verbal de-escalation programs, mental health-specific triage, and organizational cultures oriented toward alternatives to restraint significantly reduce coercive episodes without increasing adverse events. Tipo: Trabalho de Conclusão de Curso Tue, 02 Jun 2026 00:00:00 GMT https://repositorio.pucgoias.edu.br/jspui/handle/123456789/11122 2026-06-02T00:00:00Z https://repositorio.pucgoias.edu.br/jspui/handle/123456789/11085 Título: Abordagens terapêuticas na síndrome da hipersensibilidade da tosse: revisão sistemática Tipo: Trabalho de Conclusão de Curso Thu, 28 May 2026 00:00:00 GMT https://repositorio.pucgoias.edu.br/jspui/handle/123456789/11085 2026-05-28T00:00:00Z